Attached is an animated gif from
the article that shows the basic idea - a buncha cells in a fluid sample are
squeezed through a cell sized hole, one cell at a time, and they can be
switched (not shown in the figure) with an electronic charge applied to attract
or repel the various types depending on how the sorting mechanism is set up
prior to the squeeze.
Sincerely,
Rich Cooper,
Rich Cooper,
Chief Technology Officer,
MetaSemantics Corporation
MetaSemantics AT
EnglishLogicKernel DOT com
( 9 4 9 ) 5 2 5-5 7 1 2
http://www.EnglishLogicKernel.com
From: ontolog-forum-bounces@xxxxxxxxxxxxxxxx
[mailto:ontolog-forum-bounces@xxxxxxxxxxxxxxxx] On Behalf Of Rich Cooper
Sent: Monday, May 25, 2015 8:02 AM
To: '[ontolog-forum] '
Subject: [ontolog-forum] More human cell types isolated - a few pennies
each - can we make an ontology of cell types and their reaction rates?
Dear Ontologists,
My son in law is a biologist who works with a newer
technology called "flow cytology". His descriptions of the
process are insightful, and help me understand the promise of individual cell
technologies. There is an article in Technology Review which describes
the present and upcoming state of that technology:
http://www.technologyreview.com/news/537416/single-cells-analyzed-at-unprecedented-scale/
If we (Tonto) can make a total function mapping each
functional snippet of DNA to a list of biochemical reaction equations, then it
would be possible to simulate a human patient undergoing a treatment before
actually performing that treatment, just to be sure the human lives through
it.
But even more exciting is the single cell laboratory
concept where one or two ginormous molecules are squeezed into the
intracellular space - concentrate cells of that single type and we (Tonto) can
make accurate measurements of biochemical functionality for each allele.
I hope someone here knows a lot more about this
technology than I do, and can explain the promises and risks to the rest of
us.
Would an ontology of all reactive DNA to RNA to protein
sequences be useful for medicine? Not being that kind of a doctor, I
don't know, but would like to hear from the medical docs about what they
think.
Sincerely,
Rich
Cooper,
Rich Cooper,
Chief Technology Officer,
MetaSemantics Corporation
MetaSemantics AT EnglishLogicKernel DOT com
( 9 4 9 ) 5 2 5-5 7 1 2
http://www.EnglishLogicKernel.com
