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Re: [ontolog-forum] Two ontologies that are inconsistent but bothneeded

To: "'Waclaw Kusnierczyk'" <Waclaw.Marcin.Kusnierczyk@xxxxxxxxxxx>, "'[ontolog-forum]'" <ontolog-forum@xxxxxxxxxxxxxxxx>
From: "clynch" <clynch@xxxxxxxxxxxxxx>
Date: Sun, 10 Jun 2007 13:35:11 -0700
Message-id: <004d01c7ab9e$d7df8140$1500a8c0@ontoreason>
vQ,    (01)

I think Barry has straightened me out on the issue overall. I was using
infectivity as a property of physiology rather than reducing physiology to
equate to infectivity. In fact, infectivity is difficult to talk about in
terms of a single entity given that both the infecting agent and the
recipient of the infection must both have properties that interact to allow
infection to occur. An example is the issue of Parvo B19 virus infection in
humans. If the p antigen is absent on the red cell surface, the virus cannot
infect the cell, so 10% of the population is immune naturally.    (02)

Cecil    (03)

-----Original Message-----
From: Waclaw Kusnierczyk [mailto:Waclaw.Marcin.Kusnierczyk@xxxxxxxxxxx] 
Sent: Sunday, June 10, 2007 1:24 PM
To: clynch@xxxxxxxxxxxxxx; [ontolog-forum]
Subject: Re: [ontolog-forum] Two ontologies that are inconsistent but
bothneeded    (04)

clynch wrote:
> Barry,
> 
> In light of the current thinking on prions, I wonder if you might want to
> rethink the statement of
> 
> <BS> Having worked long and hard with biologists it 
> has become clear to me that the 
> continuant/occurrent distinction is the most well 
> entrenched of all the joints in nature (the 
> distinction between anatomy and physiology, for 
> example, is very old, and has not been threatened 
> one iota by recent developments in, e.g. cellular anatomy>/BS>
> 
> I think this does in fact break the long held distinction between anatomy
> (structure) and physiology, in that the only difference in the infectivity
> (physiology) of the protein is in its morphology (anatomy).    (05)

That infectivity is determined by morphology does seem to me break the 
barrier between anatomy and physiology.  And also, any microorganism 
that is infectious is so in virtue of its having a particular structure, 
I do not find this applicable to prions only.  Furthermore, you should 
probably not reduce the physiology of prions to their infectivity.  If 
we can talk about the physiology of prions at all;  Physiology is the 
study of the mechanical, physical, and biochemical functions of *living 
organisms*.    (06)

vQ    (07)



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