| Issue | AP | AV | BC | BM | BP | CM | DM | EA | EB | FO | GN | IM | IN | KB | LC | LR | MD | ML | PT | SA | SD | SG | SW | TH | TM | TX | W2 | XM | Count |
| Education | 8 | | 1 | 4 | | 2 | | | | 6 | | 1 | | | 3 | 1 | 5 | | | 5 | 7 | | 7 | 4 | 2 | 5 | 4 | 2 | 12 |
| Demonstrate utility | 4 | | | 1 | | | | 1 | | 5 | | | | | 1 | | 1 | | | 1 | 4 | | 2 | | | 3 | 1 | | 7 |
| Development methods | 3 | | 1 | | | 2 | | | 1 | | | | | | 1 | | 2 | 1 | | | 3 | | 2 | 2 | 2 | 3 | | 2 | 6 |
| De-mystifying and simplifying ontologies and ontological terminology | 3 | | | | | | | | | 2 | | | 1 | | | | 1 | | | 1 | 3 | | 4 | | | 2 | 2 | | 5 |
| Cooperation among different groups | 4 | | | 1 | | | | | | 2 | 1 | | | | | | 3 | | | 2 | 1 | | 2 | | | 2 | 2 | 1 | 4 |
| Lack of common understanding of what is meant by an ontology | 1 | | | 1 | | 1 | | | | | | | | | 1 | | 2 | 1 | | | 2 | | | 1 | 1 | 1 | | | 4 |
| Lack of expertise in ontology development | 2 | | | 1 | | | | | | 1 | | | | | | | | | | | 2 | | 2 | 1 | | 2 | 1 | | 3 |
| Difficulty of converting legacy knowledge | 1 | | | | | | | | | | | | | | | | 1 | | | | | | | 1 | | | | | 2 |
| Gap between academics and industry | | | | 2 | 1 | | | | | | | | | | | | | | | | 1 | | 1 | | | 1 | | | 2 |
| Lack of an upper ontology | 2 | | | 2 | | 2 | | | | | | | | | | | 1 | | | 1 | 1 | | 2 | 1 | 1 | 1 | 1 | 1 | 2 |
| Resistance to disruption of the status quo | 1 | 1 | | | | | 1 | | | | | | | | | | | | 1 | 1 | 1 | 1 | 1 | | | | 1 | 1 | 2 |
| Achieving balance between expressivity and computational requirements | 1 | | | | | | | | | | | | | | | | | | | 1 | 1 | | 1 | | | | | | 1 |
| Clear identification of referents | | | | | | | | | | | | | | | | | 1 | | | | 1 | | | | | | 1 | 1 | 1 |
| Difficulty and effort required for producing high quality annotations | 1 | | | 1 | | | | | | 1 | 1 | | | | | | 1 | | | | | | 1 | | | | | | 1 |
| Disagreements among experts | 1 | | | 1 | | 1 | | | | | | | | | | | | | | 1 | | | 1 | | 1 | | 1 | | 1 |
| Intractability of reasoning | 1 | | | 1 | | | | | | 1 | | | | | | | | | | 1 | 1 | | | 1 | | 1 | | | 1 |
| Lack of an open, well-maintained clearinghouse for ontologies and related products and services that are enabled by them | 1 | | 1 | | | 1 | | | | | | | | | | | | | | | 1 | | 1 | | 1 | | | | 1 |
| Lack of motivation to create a standard | 1 | | | | | | | | | 1 | | | | | | | | | | | | | 1 | | | | 1 | | 1 |
| Lack of ontologies for various domains | | | | | | | | | | 1 | | | | | | | | | | | 1 | | 1 | | | | | | 1 |
| Lack of tools | | | | | | | | | | | | | | | | | | | | | 1 | | 1 | 1 | | 1 | | | 1 |
| Reusability of ontologies | | | | 1 | | | | | | | | | | | | | | | | | | | 1 | | | 1 | | | 1 |
| Should not be left to the logic of the mathematicians | 1 | | | | | | | | | | | 1 | | | 1 | | 1 | | | 1 | 1 | | 1 | | | 1 | 1 | | 1 |
| Slow rate of adoption | | | | 1 | | | | | | | | | | | | | | | | | | | 1 | | | | | | 1 |
| Tool incompatibilities | 1 | | | 1 | | | | | | 1 | | | | | | | | | | | 1 | | 1 | | | | | | 1 |
| Unification of data and exploitation the unified data | 1 | | | | | | | | | | | | | 1 | | | | | | 1 | 1 | | | | | | | | 1 |